(6-CHLORO-2-PYRIDINYL)BORONIC ACID - Names and Identifiers
(6-CHLORO-2-PYRIDINYL)BORONIC ACID - Physico-chemical Properties
Molecular Formula | C5H5BClNO2
|
Molar Mass | 157.36 |
Density | 1.41 |
Boling Point | 355℃ |
Flash Point | 169℃ |
Vapor Presure | 1.17E-05mmHg at 25°C |
pKa | 6.82±0.53(Predicted) |
Storage Condition | Inert atmosphere,Store in freezer, under -20°C |
Refractive Index | 1.559 |
(6-CHLORO-2-PYRIDINYL)BORONIC ACID - Introduction
(6-chloropyridin-2-yl)boronic acid is an organic compound whose chemical formula is C5H4BClNO2. The following is a description of the properties, uses, preparation and safety information of the compound:
Nature:
-Appearance: Colorless to light yellow solid;
-Solubility: Soluble in some organic solvents, such as dimethyl sulfoxide and ethanol;
-Melting point: about 180-185°C.
Use:
(6-choropyridin-2-yl) boronic acid is an important organic synthesis intermediate, commonly used in organic chemical synthesis reactions. It can be used as a substitute reagent for aromatic compounds and is used in the synthesis of various organic compounds, such as drug molecules, pesticides and coating materials.
Preparation Method:
(6-chloropyrin-2-yl) The preparation method of boronic acid is usually to use boric acid and 2-chloro-6-pyridine borate (2-chloro-6-boronopyridine) as raw materials, and obtain the product through appropriate reaction conditions. The specific preparation method can be adjusted according to specific requirements and reaction conditions.
Safety Information:
- (6-choropyridin-2-yl) boronic acid is generally considered to be less harmful to human body and environment, it is still necessary to pay attention to the correct operation and storage methods of chemicals;
-When using the compound, it is recommended to wear appropriate protective equipment, such as gloves, glasses, etc., to prevent skin contact and aspiration;
-The compound may be irritating to the eyes and respiratory system. If it comes into contact with skin or eyes, rinse with plenty of water and seek medical help;
-Keep away from fire and oxidant during use and storage to avoid fire or explosion.
Last Update:2024-04-09 15:17:59